< Previous46 M I S S OU RI : M A K I NG . G R O W I NG . MO V I NG .Led by St. Louis, Missouri is boosting its profi le as a hub of innovation.AG T E C HAgtech, the intersection of agriculture and technology, includes research into plants and animals and the development of machines and chemicals to improve farming. Simple enough, at least by de nition,But in practice, agtech requires deep dives into disciplines as esoteric and wide-ranging as plant genomics, digital data collection and management, infectious diseases, biotechnology, seed development, renewable energy and even drone technology.Peel away at agtech’s many layers, and much of what you’ll see occurs within a few square miles of St. Louis, Mo.“No other metro area in the world,” reads a recent market assessment by the Brookings Institution, “can boast the scope and expertise of St. Louis’ agtech/food tech sector.” St. Louis, says Brookings, is uniquely positioned to promote itself as the “global bio solutions epicenter.”“Agtech is St. Louis’s fastest growing sector,” says Sheila Sweeney, chief executive o cer of the St. Louis Economic Development Partnership (SLEDP), the joint agency that promotes business growth in St. Louis and St. Louis County. “We have,” says Sweeney, “an extraordinary pool of talent working in this sector.” at talent resides within a cluster of institutions that’s becoming bigger and more bountiful by the year. It includes Monsanto, the multi-national ag giant; the Donald Danforth Plant Science Center, an internationally recognized research lab considered the city’s center by G A R Y DAU G HTE R S39 North is an ambitious e ort to help solidify St. Louis as a hub for agriculture technology.Photo by Flickr/Danforth Plant Science Centerof agtech innovation; BRDG (Bio Research & Development Growth) Park, home to 10 emerging scientific enterprises including firms from Germany, Israel and India; and Helix Center BioTech Incubator, which is owned and operated by SLEDP.Those ventures are the primary threads in a commercial, entrepreneurial and residential tapestry being woven in the St. Louis section of Creve Coeur. It’s what a lot of cities talk about. Connectivity. In St. Louis, it’s happening in the agtech space through a 10-year project called 39 North.Spearheaded by St. Louis County Executive Steve Stenger, 39 North is an effort to physically link the city’s agtech assets through corridors of greenspace, residential property and businesses. A mix of city planning and business development, the project’s master plan was funded by a $500,000 grant from the US Department of Commerce. The driving idea behind it is to create new jobs and lure top-notch talent through enhanced livability.“I believe 39 North is going to generate thousands of jobs for St. Louis County and our region,” says Stenger. “And I think it is going to be a place and a space where people come to share ideas. Where they come to collaborate.”The name 39 North pays homage to the idea that the 39th parallel of north latitude runs not only through St. Louis, but also connects the world’s great agricultural belts. Backers of the project envision 400 new residential units, more than a half-million sq.-ft. of office space and 85,000 sq.-ft of retail to help solidify the ag cluster’s identity and livability.The inclination of agtech startups to flee for the coasts after establishing themselves in St. Louis has been a source of frustration in the past. 39 North is seen as a way to position the city favorably relative to the coastal tech darlings.Keith Duncan, a research scientist at the Danforth Center, believes 39 North will promote added value within the area’s burgeoning agtech cluster.“All the facilities that are now in the area will be bikeable, walkable, hikeable, runnable. It’s going to be a fantastic place to be. It’s going to make working hard very easy.”Missouri’s Statewide Agtech LeadershipMissouri’s robust food production sector includes nearly 400 companies, with some of the top 100 food producers among them. PepsiCo, Tyson Foods, Nestle, Kraft Heinz, Coca-Cola, Anheuser Busch and General Mills each have food solutions facilities in Missouri. The state’s agriculture industry contributes $33 billion in GDP to Missouri’s economy and generates $88 billion in sales and more than 378,000 jobs.Kraft Heinz, in 2017, cut the ribbon on a $250 million expansion of its cold cuts facility in Kirksville, and announced months later that employment at the plant had doubled over the previous year to 900 employees; the plant has an output of nearly one million packages daily. PepsiCo, in 2017, opened a new distribution center that brought 75 new jobs to Poplar Bluff. Ajinomoto Windsor, also in 2017, announced plans for a frozen appetizer production plant in Joplin. The $39 million investment is to create an expected 200 jobs.Missouri has the sixth-largest highway system in the US, and being at the nation’s geographic crossroads, the state is within 500 miles of 43-percent of the US population. Colorado-based Aurora Organic Dairy cited Missouri’s central location as crucial to its decision to construct its second diary in Columbia.“Columbia was the best choice,” says Aurora’s founder and CEO Mark Peperzak, “because it offers a location that expands and improves the efficiency of our supply chain.”In May, 2017, Aurora broke ground on its $141 million Columbia facility, which is expected to create 90 jobs to start, with the possibility of up to 150 new jobs over the next five years. 48 M I S S OU RI : M A K I NG . G R O W I NG . MO V I NG .AF O OD S OL U T I ON Ss the geographic center of the nation’s population, Missouri lies at the crossroads of America’s food and food production sectors. The Show Me State is home to nearly 100,000 farms, second-most in the nation, covering 28.3 million acres.In 2016, agriculture and related industries contributed more than $88 billion in sales and more than 378,000 jobs in Missouri, according to the Missouri Department of Agriculture. The state plays a leading role in the nation’s production of agricultural products and ranks fourth for rice acres harvested, ninth for soybean acres harvested, 10th for corn acres planted, third for beef cows and seventh for hog sales.Missouri’s food production sector also includes nearly 400 companies, including household names such as Tyson, Kraft, Budweiser, Nestlé and Con Agra.General Mills launched operations in the famed town of Hannibal on the Mississippi River in 2001 and today is a major jobs provider, employing about 1,000 people with an annual payroll of $80 million. A $65-million expansion of the plant, now being completed, will make it among the company’s biggest US food production facility and the sole worldwide supplier of Progresso Soup.“The plant will continue to make Progresso Soups, Hamburger Helper, Old El Paso, and Fiber One and Nature Valley Granola bars,” the company says in a statement, adding that “General Mills is a proud member of the Hannibal community. We’re excited to continue to grow and work with our talented workforce in Hannibal.”The Hannibal expansion was enabled through the city’s issuance of industrial development bonds to fund $7 million in property improvements and $58 million in new equipment. The investments will help the company to build a third soup line at the plant.“I’m proud of General Mills for thinking enough of our community to put more dollars into it,” says Hal Benedict, a member of the Northeast Missouri Economic Development Council.“The Best Choice”Colorado-based Aurora Organic Dairy, a leading producer of organic milk and butter, is making a massive investment in the heart of Missouri, having broken ground on a $141 million milk plant, the company’s second, to be completed next year in Columbia. “Columbia was the best choice,” says Marc Peperzak, founder and CEO, “because it offers a location that expands and improves the efficiency of our total supply chain from organic feed, to milk, to consumer.”Missouri is a food production powerhouseby G A R Y DAU G HTE R SAFEAST OF PLENTYFEAST OF PLENTYImage courtesy Missouri PartnershipM I S S OU RI : M A K I NG . G R O W I NG . MO V I NG . 49The plant is expected to bring 150 new, full-time jobs to the area, which lies directly between Kansas City and St. Louis.“This is a great addition to the Columbia region,” says Steve Johnson, CEO of Missouri Partnership, a public-private economic development partnership. “Food solutions,” says Johnson, “is a key strength for Missouri due to our robust food production sector and our leading role in agriculture.”California-based Ajinomoto Windsor, a leading company in the frozen food industry, is another out-of-state firm that recognizes Missouri’s food production prowess. The company, which staked out a presence near Joplin more than 20 years ago, is set to open a new frozen appetizer production plant in the city. The $39-million investment is expected to create up to 240 new jobs.Frick’s Quality Meats began as a butcher shop in Washington, Missouri, in 1896. From that humble beginning, the family-owned business has grown to a nationally known brand with retail distribution to 44 states and a 120,000-sq.-ft. facility that makes smoked meats and sausages. In late 2017, Frick’s broke ground on an 18,000-sq.-ft. expansion, an $8-million investment expected to bring 40 new jobs to the town just west of St. Louis. The expansion will facilitate the company’s move into organics.“We look forward to the opportunities the expansion brings,” says fifth-generation owner Dave Frick, “including meeting the growing demand of our customers and the launch of Frick’s Natural and Organic Products.”Something Big is BrewingMissouri is home to more than 130 wineries, 50 craft breweries, and 20 distilleries and the world-famous Budweiser family of beers. Budweiser parent, Anheuser-Busch, announced 2017 investments in its St. Louis brewery and its bottling plant in Arnold totaling more than $20 million. The state’s top craft breweries include Kansas City Bier Company, Boulevard and Martin City Brewing company in Kansas City; 4 Hands Brewing Co., Schlafly and Perennial Artisan Ales in St. Louis; Logboat Brewing Company in Columbia; and Mother’s Brewing Company in Springfield. Mother’s offers a handful of beers, including “Foggy Notion” and “Rye Barrel Milf,” that come with a hefty alcohol-by-volume content of 11-percent.Brick River Cider, which opened in a converted firehouse in St. Louis in October, is the city’s first dedicated cider works. The company supports local agriculture by exclusively using fresh Midwestern apples.“Our ciders,” says the company, “range from classic and traditional to bold and innovative, but whatever style they are all 100 percent gluten-free from fresh, pressed regional fruit, never concentrate.”Other recent food and beverage industry investments include:• An 82,000-sq.-ft. facility by Texas-based egg producer Vital Farms. The $13-million project is expected to bring 50 new jobs to the Springfield area.• A 12,000-sq.-ft. expansion of the Triumph Foods pork processing plan in St. Joseph. Triumph employs more than 2,700 workers at the plant.• •Ohio-based SugarCreek, producer of raw and cully cooked foods, plans to create 70 new jobs by expanding its 10-year-old plant in Carthage.• Nestlé USA announced plans to add as many as 300 technology jobs in St. Louis by moving its IT operations there from California. BEEF COWS - 3RD1.9 million headBROILER CHICKENS - 9TH294 million headCORN - 10TH294 million bushelsCOTTON - 8TH400,000 balesHOGS - 7TH3 million headRICE - 4TH12 million cwtSOYBEANS - 9TH181 million bushelsTURKEYS - 5TH19 million headMISSOURI’S AG COMMODITIES US RANKINGSSource: Missouri Department Of AgricultureH E A L T H I N N O V A T I O N A N D B I O S C I E N C E I N M I S S O U R Irom cutting-edge medical treatments to seamless electronic record keeping, Missouri’s innovative health care companies are changing the industry’s landscape around the world. Some of the world’s most prestigious hospitals, medical schools and health care companies call the Show Me State home. Across the state, colleges and universities o er degrees in biological and biomedical sciences. Some , people are employed in the bioscience industry with more than , companies. e Missouri Biotechnology Association ranked the Kansas City region as the fth per capita in clinical trials. And another study conducted by Harvard Business School ranked the state at No. for employment in biopharmaceuticals. Companies like P zer, Ascension Health, Cerner, Centene Corporation, Express Scripts and many other health innovation companies call the state home and propel its reputation as a bioscience and health care leader forward. In St. Louis, Mercy Hospital opened the rst Virtual Care Center in the world. With little more than a computer and broadband access, Missouri’s bioscience and health innovation companies are leading the way to life saving research and scientifi c advancements.by S AVAN NAH K I N GFHALE & HEARTYpatients can be seen by physicians and receive the care they need. e four-story, , -sq.-ft. center provides remote support for patients in their homes, in a physician’s o ces or an emergency room. e center is also a hub for the hospital system’s telemedicine program including Mercy SafeWatch, which allows hospital sta to monitor patient vital signs in intensive-care units in ve states. Since it opened, the center has witnessed a percent decrease in the length of patient stays and percent fewer deaths than expected. e St. Louis hospital is the rst in the Mercy system to be certi ed by the Healthcare Information and Management System Society as one of the world’s most technological advanced hospitals.Growth: Symptom of a Healthy EcosystemSeveral new expansions and relocations have been recently announced in Missouri including Spring Venture Group’s new headquarters in Kansas City, Missouri. e direct-to-consumer distributor of Medicare supplement insurance has moved into its new 50 M I S S OU RI : M A K I NG . G R O W I NG . 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M I S S OU RI : M A K I N G . G R O W I N G . M O V I N G .In St. Louis, Centene Corp. broke ground in April on its new $ -million expansion. e company is the nation’s largest managed care company and currently employs , people at its global headquarters in St. Louis. BlueStrata EHR, an electronic health record system company, invested $ , and created new high-paying jobs in Creve Coeur, just outside of St. Louis. “Missouri has built a global reputation as a center of innovation and entrepreneurship,” said Tony Coco, president and CEO of BlueStrata EHR. “ e state’s highly educated workforce, favorable business climate, along with local funding from Cultivation Capital give us con dence that Missouri is the right location for BlueStrata.” e state’s animal health and agtech companies are also ourishing. Aptimmune Biologics chose to relocate its headquarters from Champaign, Illinois to St. Louis’ North innovation district and the Bio Research & Development Growth (BRDG) Park in January. e company, which specializes in developing vaccines for the swine industry, noted nancial and logistical support from investors and businesses in St. Louis as a large basis for its decision. In St. Joseph, Boehringer Ingelheim invested $ million in its largest animal health manufacturing operation. e company’s , -sq.-ft. expansion adds on to its , -sq.-ft. campus where it produced livestock animal vaccines. e expansion is expected to create new jobs and to be completed in . Missouri Health Innovation CompaniesSt. JosephJoplinSpringfieldLebanonKennettJefferson CitySt. LouisMexicoKirksvilleWarrensburgKansas CityMaryvilleMoberlyColumbiaMarshallSedaliaWest PlainsPoplar BluffFarmingtonCape GirardeauFort Leonard Wood!(!(§¨¦49§¨¦70§¨¦44§¨¦55§¨¦35§¨¦57§¨¦29§¨¦64§¨¦72£¤65£¤60£¤61£¤36£¤67£¤54£¤50£¤160£¤59£¤136£¤62£¤40£¤63£¤71£¤160£¤169£¤24((((((((((((((((((!!!!!!!!!!!!!!!!!((!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! !!!!!!!!!!!!!!!591046382711 1053792648Health innovation companiesAnimal food companiesVeterinary pharmaceutical companiesMissouri Health Innovation CompaniesSt. JosephJoplinSpringfieldLebanonKennettJefferson CitySt. LouisMexicoKirksvilleWarrensburgKansas CityMaryvilleMoberlyColumbiaMarshallSedaliaWest PlainsPoplar BluffFarmingtonCape GirardeauFort Leonard Wood!(!(§¨¦49§¨¦70§¨¦44§¨¦55§¨¦35§¨¦57§¨¦29§¨¦64§¨¦72£¤65£¤60£¤61£¤36£¤67£¤54£¤50£¤160£¤59£¤136£¤62£¤40£¤63£¤71£¤160£¤169£¤24((((((((((((((((((!!!!!!!!!!!!!!!!!((!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! !!!!!!!!!!!!!!!591046382711 1053792648Health innovation companiesAnimal food companiesVeterinary pharmaceutical companies“Missouri has built a global reputation as a center of innovation and entrepreneurship. … The state’s highly educated workforce, favorable business climate, along with local funding from cultivation Capital, give us confidence that Missouri is the right location for BlueStrata.”— Tony Coco, president and CEO of BlueStrata EHR, sq. ft. headquarters downtown and expects to add , new jobs over the next six years. Cerner, a health care information technology company also chose Kansas City to expand its headquarters. e $ . -billion expansion in the south Kansas City area is expected to house some , employees when it is completed. e company is also expanding its , -sq.-ft. North Kansas City demonstration center to the tune of $ million. “Cerner’s success continues to re ect its growth in the Kansas City area,” said Victoria Rosengarten, a company representative. “ is expansion will serve as an additional avenue to highlight our solutions, emphasize our mission and re ect our culture.”Deck.HEADLINEM I S S OU RI : M A K I NG . G R O W I NG . MO V I NG .53t. Louis’ bioscience cluster was ranked the sixth largest in the nation – ahead of Boston, Cleveland and San Diego – by the National Cluster Mapping Project. As home to major life science companies like Monsanto, Express Scripts, and world-renowned research institutions like Washington University in St. Louis and e Donald Danforth Plant Science Center, the city has built one of the strongest bioscience and agtech clusters in the country. Sheila Sweeney, CEO of St. Louis Economic Development Partnership notes the region’s talent assets, infrastructure, central geographic location and innovation districts help drive St. Louis forward. Sweeney says one of her top priorities is to continue to enhance the agriculture and agtech sector and attract new companies to the region focusing on research and technology, plant science, crop yield, drone technology and contract research – an easy sell when you consider the people working in St. Louis. “We really have a highly educated and talented workforce,” Sweeney says. “I think our best kept secret is that we graduate 44,000 students from area universities and colleges every year. At 39 North we have 1,000 plant science PhDs. ey’re all working and living here, and that talent continues to grow.”St. Louis has one of the most well-educated workforces in the country with a Bachelor’s degree attainment nearly 10percent higher than the national average and those educated minds are brimming with new ideas. According to Popular Mechanics and Mashable, St. Louis is the No. 1 fastest-growing market for tech startups in the country.“We are seeing a lot of high growth startups in bioscience and agtech,” says Ginger Imster, Vice President of Innovation and Entrepreneurship for St. Louis Partnership. “What we hear from them is that they like St. Louis because they can collaborate with other innovators. One of the things that makes St. Louis unique is that we have three thriving innovation districts that all work together and feed o the energy from one another.”If St. Louis is at the heart of the country’s bioscience industry, then BioSTL is its backbone. BioSTL is a non-pro t organization with support from a coalition of universities, businesses and philanthropic leaders that supports the region’s bioscience and innovation ecosystem. Founded in 2001 as the Coalition for Plant and Life Sciences, BioSTL fosters collaborations to bene t the region’s St. Louis is a Global Leader in Bioscience, Agtech and Innovation.by S AVAN NAH K I N GI N V E S TM E NT P R O F I L E : S T . L O U I S E C O N O M I C D E V E L O P M E N T P A R T N E R S H I P & B I O S T LINNOVATION CITYINNOVATION CITYThe BioGenerator Labs is one of St. Louis’ many assets for entrepreneurs and will nearly triple in size and graduate space for growing companies in 2019.Photo courtesy of BioSTLINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITYINNOVATION CITY54 M I S S OU RI : M A K I NG . G R O W I NG . MO V I NG .bioscience community. St. Louis’ strong university and corporate presence have been a boon for R&D for many years, and the coalition has strengthened the scienti c community. Put simply, it’s designed to provide everything this ecosystem needs to thrive. “St. Louis is a city built by entrepreneurs with bold ideas,” says Donn Rubin, President and CEO of BioSTL. “From Anheuser-Busch brewing beer, Enterprise o ering cars for rent, and Ralston Purina recognizing pets as part of our family, to McDonnell Douglas technology leading America’s rst human space ight program, and Monsanto helping farmers to produce food to feed the world. But over time, we lost that entrepreneurial edge as more people went to work for big corporations and then those big corporations consolidated. Yet, we had tremendous intellectual capital within our great universities, medical schools and research institutions. e problem was, an entrepreneurial support system didn’t yet exist in St. Louis, so we became a farm system for California or the East Coast.”The Comeback In 2009, P zer laid o hundreds of researchers at its St. Louis facilities. When faced with the ood of displaced scientists and business people, BioSTL rallied local bioscience companies to hire as many as possible. e civic group then took its e orts a step further and began encouraging these same scientists to pursue their own business ideas by scaling up its startup accelerator BioGenerator, the investment arm of BioSTL.BioGenerator helps promising companies in the region reach their potential and bring their products and services to market sooner. Since it was formed in 2003, BioGenerator has invested nearly $19 million in more than 70 high-growth ventures. ese investments have attracted $509 million in additional funding from outside investors. One of the rst companies to take advantage of the newly formed non-pro t accelerator and seed investor was Con uence Life Sciences Inc., whose founders, Walter Smith and Joe Monahan, had worked with a team of scientists focused on anti-in ammatory drugs while at P zer. “Joe and I are both research scientists. Neither of us had much business experience and we’re not necessarily entrepreneurial, or considered ourselves to be entrepreneurs,” says Walter Smith, co-founder and Senior Vice President of R&D for Con uence. “But we had some, what we thought, were really good ideas to create new drugs and Ariel Rendering of 39 NorthPhoto courtesy of Danforth Plant Science CenterM I S S OU RI : M A K I NG . G R O W I NG . MO V I NG .55we learned on the job through working with BioGenerator how new entities get formed and funded and grow.”Seeing the potential in their ideas, BioGenerator, along with about $500,000 from the state’s Missouri Technology Corp., built a shared lab space with equipment for the new company in the Cortex Innovation Community, St. Louis’ nationally-recognized urban innovation node for technology and bioscience research. Today, BioGenerator’s free labs there house some 50 science-based companies with more than 150 employees. In August 2017, BioGenerator and Con uence both realized the fruits of their labors with the $100-million acquisition of Con uence by Pennsylvania-based, dermatologist-led biopharmaceutical company Aclaris erapeutics Inc. And, by the way, with all the continued growth in St. Louis, it may not come as a surprise that the pharma giant has changed gears, making a major comeback in the region. P zer is building a state-of-the-art R&D and process development facility in Chester eld, Missouri. e 295,000-sq.-ft. facility is expected to be completed in 2019 and will be home to the company’s Bio erapeutics Pharmaceutical Sciences group. e new facility will bring more than 450 area employees together under one roof and the company has plans to hire 80 more employees over the next few years. “We’ve been proud to call Missouri home since 2002,” said John Ludwig, Senior Vice President of Bio erapeutics Pharmaceutical Sciences for P zer. “During this time, we’ve bene tted from the excellent life sciences workforce based in Missouri, and also from a strong partnership with the State, St. Louis County, and the St. Louis Economic Development Partnership. All of these were important factors as we sought a new home where we could continue to evolve our business over the coming years.”With innovation hubs like Cortex, 39North and T-REX, it’s no wonder small businesses are growing like weeds in the region. • Cortex: A 200-acre innovation hub and technology district located in St. Louis’ historic Central West End. e Live-Work-Play-Learn biomedical district was formed in 2002 when BioSTL convened stakeholder institutions that now anchor the district: Washington University, BJC Healthcare, University of Missouri — St. Louis, St. Louis University and the Missouri Botanical Garden. More than 350 companies are in the Cortex Innovation Community. • 39 North: With the highest concentration of plant science PhD’s in the world, St. Louis’ newest innovation district, 39 North — named for the agricultural belt around the world — is a natural next step for innovation. Located next door to Monsanto’s global headquarters and the Danforth Plant Science Center, the district is anchored around plant science and agtech. • T-REX: A coworking space and technology incubator in downtown St. Louis. Since its inception in 2011, T-REX has created 3,497 jobs in the city and sees a total annual economic output of more than $464 million. e incubator is home to more than 200 companies which includes 180 startups, as well as several entrepreneur support organizations. Janet Wilding, Vice President of Major Projects and 39 North for the St. Louis Economic Development Partnership, says St. Louis County has invested a “I think our best kept secret is that we graduate 44,000 students from area universities and colleges every year. At 39 North we have 1,000 plant science PhDs. They’re all working and living here, and that talent continues to grow.” — Sheila Sweeney, CEO of St. Louis Economic Development PartnershipNext >